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  • Pracownicy Uniwersytetu Łodzkiego

dr

Karolina Kowalczyk

POSITION:
chemist, scientific-technical employee
Laboratory of Molecular Spectroscopy, Faculty of Chemistry
e-mail: karolina.kowalczyk@chemia.uni.lodz.pl
  • Job description
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Job description

chemist, scientific-technical employee

Laboratory of Molecular Spectroscopy

  • Performing/Recording NMR Spectra
  • Technical Maintenance of NMR Spectrometers (Avance III and AvanceNeo Spectrometer equipped with a Prodigy cryoprobe), including refilling cryogenic liquids (liquid nitrogen and liquid helium)
  • Administrative Support Related to Conducted Analyses
  • Conducting Scientific Research

  • Bio

    University of Lodz,  10/2017 – 12/2024 

    • Doctoral Studies: Chemistry 

    Dissertation title: Synthesis and biological studies of organometallic conjugates of kinesin-5 inhibitors 5 


    University of Lodz, 10/2015 - 06/2017 

    • Master’s Degree: Chemistry in Science and Industry

    Dissertation title: Synthesis of metallocene analogs of selected anti-mitotic compounds 


    University of Lodz,  10/2013 - 09/2015

     • Bachelor’s Degree: Chemistry in Science and Industry

     Dissertation title: Polymerization activators and inhibitors of tubulin

    Achievements


    · Karolina Kowalczyk, Andrzej Błauż, Krzysztof Krawczyk, Błażej Rychlik, Damian Plażuk Design and Synthesis of Ferrocenyl 1,4-Dihydropyridines and Their Evaluation as Kinesin-5 Inhibitors,

     Dalton Trans., 2024, 53, 16038-16053 


    · Karolina Kowalczyk, Andrzej Błauż, Daniel Moscoh Ayine -Tora, Christian G. Hartinger, Błażej Rychlik, Damian Plażuk, Design, Synthesis, and Evaluation of Biological Activity of Ferrocene-Ispinesib Hybrids: Impact of a Ferrocenyl Group on the Antiproliferative and Kinesin Spindle Protein Inhibitory Activity, Chem.Eur. J., 2023, 29, e202300813 


    · Anna Wieczorek-Błauż, Karolina Kowalczyk, Andrzej Błauż, Anna Makal, Sylwia Pawlędzio, Chatchakorn Eurtivong, Homayon J. Arabshahi, Jóhannes Reynisson, Christian G. Hartinger, Błażej Rychlik, Damian Plażuk, Impact of the ferrocenyl group on cytotoxicity and KSP inhibitory activity of ferrocenyl monastrol conjugates Dalton Trans., 2022, 51, 491-508 


    · K. Kowalczyk, A. Błauż, W. Ciszewski, A. Wieczorek, B. Rychlik, D. Plazuk,. – Colchicine metallocenyl bioconjugates showing high antiproliferative activities against cancer cell lines, 

     Dalton Trans., 2017, 48, 17041-17052


     · D. Plażuk, A. Wieczorek, W. M. Ciszewski, K. Kowalczyk, A. Błauż, S. Pawlędzio, A. Makal, C. Eurtivong, H. J. Arabshahi, J. Reynisson, C. G. Hartinger and B. Rychlik, Synthesis and in vitro Biological Evaluation of Ferrocenyl Side-Chain-Functionalized Paclitaxel Derivatives, ChemMedChem, 2017, 12, 1882–1982


    Office hours

    chemist, scientific-technical employee

    Laboratory of Molecular Spectroscopy

    Tamka 12 room: 4-221 91-403 Łódź

    Contact

    chemist, scientific-technical employee

    Laboratory of Molecular Spectroscopy

    phone: 42-635-57-56

    phone: 42-635-57-54

    www:

    Tamka 12 91-403 Łódź room: 4-221

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